Feline Hepatic Disease
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چکیده
Clinicopathologic changes in the course of liver diseases are as variable and nonspecific as the physical findings, nevertheless liver disease is often first diagnosed during routine blood tests. It is particularly important to distinguish between enzyme diagnostics and liver function tests. Increased activities of „liver enzymes“ are either due to liver cell damage (ALT, AST, GLDH) or enzyme induction (AP, GGT) caused by cholestasis or by drugs. There are also a number of extrahepatic conditions that cause increases in enzyme activities. However, enzyme elevations don’t provide any information on the degree of liver damage or liver function To evaluate the function of the liver, concentrations of substances are measured, which are synthesized or metabolised in the liver, and/or excreted by the liver/bile (bilirubin, bile acids, albumin, coagulation factors, urea, glucose).
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